The Montreal Heart Institute is currently recruiting patients for a Phase-IIc clinical trial that is evaluating the safety of PulmoBind in participants with pulmonary hypertension and its potential to detect abnormal pulmonary circulation associated within pulmonary hypertension. (ClinicalTrials.gov Identifier: NCT02216279). Pulmonary hypertension is a condition that causes gradual loss…
Dublin, Ireland-based pharmaceutical company Actavis plc has submitted an Abbreviated New Drug Application (ANDA) to the U.S. Food and Drug Administration (FDA) regarding its generic version of the drug Letairis, originally marketed by Gilead Sciences, Inc. The company is now waiting for the decision from the FDA on…
A research team from Brigham and Women’s Hospital (BWH) recently made significant advances in understanding what causes Pulmonary hypertension (PH). The study published in the journal EMBO Molecular Medicine has important implications for the diagnosis, treatment, and prevention of PH in people at-risk of developing the disease.
The Pulmonary Hypertension Association (PHA) has publicly announced its support for the Patients’ Access to Treatments Act (PATA), which is currently being debated in the U.S. House of Representatives. The bi-partisan legislation was presented last week by representatives David B. McKinley (R-WV) and Lois Capps (D-CA) and is designed to reduce…
A recent study published in the journal PLoS One found that a single dose of Sildenafil is not associated with clinical improvement of right ventricular (RV) function as measured by cardiovascular magnetic resonance (CMR) in patients with PH-related heart failure (HF). Heart failure…
A new study recently published in The Journal of Heart and Lung Transplantation demonstrated the accuracy and utility of a risk score calculator to predict the one-year survival in patients with pulmonary arterial hypertension. The study is entitled “Prognostic implications of serial risk…
The Pulmonary Hypertension Association (PHA) is organizing another edition of its monthly Patient Telephone Support Group to help people diagnosed with pulmonary hypertension meet other patients and deal with the isolation and burden associated with the disease. This month, the meeting is taking place on March…
A research team from the VU University Medical Center in Amsterdam, the Netherlands recently found that using a combination of assessments for ventricular pressure and pulmonary artery (PA) improves the likelihood of detecting pulmonary hypertension (PH) in patients assessed with computed tomography pulmonary angiography (CTPA). In their study, Onno…
Inhaled Nitric Oxide (iNO) is an FDA approved drug used both in term and near-term neonates suffering from respiratory failure due to pulmonary hypertension. Despite the fact that the drug does not offer clinical benefit in preterm neonates, iNO is still prescribed for these patients, according to a study of researchers…
Findings from a recent study presented this week during the American College of Cardiology/i2 Scientific Session revealed that denervation of the pulmonary artery through catheterization led to a decline in pulmonary arterial hypertension (PAH)-related events and an improvement in heart function and hemodynamic variables in patients with pulmonary hypertension. The…
Researchers at the Cleveland Clinic recently published findings in the journal Circulation revealing that a protein linked to the glucose metabolism pathway can promote cellular proliferation in lung tissues of individuals with idiopathic pulmonary arterial hypertension (IPAH). The study is entitled “O-GlcNAc Transferase…
Results from a recent study published in the Egyptian Journal of Chest Diseases and Tuberculosis suggest that Pulmonary hypertension (PH) in patients with Chronic Obstructive Pulmonary Disease (COPD) is a common co-morbidity along with right sided cardiac changes. Based on the findings, the researchers suggest that…
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