News

Early Renal Denervation Improves Pulmonary Hypertension and Survival Rate, Animal Study Shows

Early renal denervation (RDN) treatment improved pulmonary arterial hypertension (PAH) in a rat model, a new study from China showed. The study titled, “Effects of renal denervation on monocrotaline induced pulmonary remodeling,” was published in the journal Oncotarget. Despite the progress achieved with oral therapies over the last two decades, the prognosis…

Doctors Are Doing Inadequate Job of Screening Scleroderma Patients for PAH, Study Concludes

Scientists have long known that people with scleroderma are at increased risk of developing pulmonary arterial hypertension. But many with scleroderma whom doctors suspect of having PAH are not receiving optimal screening for the respiratory condition, a study concludes. Nor are enough scleroderma patients suspected of having pulmonary hypertension being referred for tests that…

Pulmonary Hypertension Therapy Developer MannKind Retains Biopharma Financing Specialist

MannKind Corporation, which is developing the pulmonary arterial hypertension (PAH) therapy Treprostinil Technosphere, has retained the biopharmaceutical financing specialist Locust Walk to help it raise capital for Treprostinil and other projects. Locust Walk lines up investors and strategic partners for companies like MannKind, which also wants to use its Technosphere technology to develop…

Sixty Pulmonary Hypertension Patients Receive Implanted-pump Therapy-delivery Systems

Researchers implanted a long-term, intravenous therapy-delivery system consisting of internal pumps and catheters in 60 pulmonary arterial hypertension (PAH) patients, according to a clinical trial. The IV infusion system, developed by Medtronic, delivers Remodulin (treprostinil). The research team said the system should be easier to use than current therapy-delivery methods.

Patients Undergoing Spleen Removal Face Higher Risk of PH and Cardiovascular Complications, Danish Study Shows

Patients who undergo splenectomy, or surgery to remove the spleen, increase their risk of pulmonary hypertension (PH), myocardial infarction and stroke. That’s the conclusion of a study, “Risk of cardiovascular events and pulmonary hypertension following splenectomy – a Danish population-based cohort study from 1996-2012,” that appeared in the journal Haematologica.

Short Survival of Only 4 Years Still Characterizes Systemic Sclerosis Patients with PAH, Australian Study Finds

The average systemic sclerosis (SSc) patient burdened with pulmonary arterial hypertension (PAH) lives only four years after diagnosis, finds an Australian study,  “Survival and quality of life in incident systemic sclerosis-related pulmonary arterial hypertension,” that appeared in the journal Arthritis Research & Therapy. PAH is a serious…

Depression More Likely in Chronic Thromboembolic Pulmonary Hypertension Patients, Study Finds

People with chronic thromboembolic pulmonary hypertension (CTEPH) are more likely to have a depressive temperament, finds a Japanese study, “Depressive Status in Patients With Chronic Thromboembolic Pulmonary Hypertension” that appeared in the Circulation Journal. CTEPH is a progressive disease characterized by increasing pulmonary vascular resistance. Although the underlying…

Chloe Temtchine Concert Draws Thousands of Viewers and Attention to Pulmonary Hypertension

A live, online mini-concert starring Chloe Temtchine has drawn thousands of viewers while raising awareness about pulmonary hypertension (PH), a progressive, life-threatening disease. The Facebook Live concert, presented recently by the Pulmonary Hypertension Association (PHA), attracted 1,500 live attendees and served as the finale for PHA’s World PH Day, the culmination…

Specific Stem Cells May Contribute to Pulmonary Hypertension, Vanderbilt Study Finds

Stem cells known as mesenchymal progenitor cells (MPCs) may contribute to the blood vessel anomalies causing pulmonary hypertension (PH), says a new study,  “Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction,” that appeared in the Journal of Clinical Investigation. Vascular anomalies in the lung are…