News

In a recent collaborative research project published in the PLOS one journal entitled “Risk Factors of Pulmonary Hypertension in Brazilian Patients with Sickle Cell Anemia,” researchers suggest that patients suffering from sickle cell anemia (SCA) have higher risks for developing pulmonary hypertension (PH). Sickle-cell…

Reata Pharmaceuticals has announced that it will present Phase 2 results from a trial of its investigational therapy bardoxolone methyl in treating pulmonary arterial hypertension (PAH). The study’s findings will be presented October 27, 2015 at the 2015 American College of Chest Physicians (CHEST) annual meeting in Montreal, Canada in a…

Cytori Therapeutics recently published a report of 12-month data from the Scleradec-I clinical trial studying hand dysfunction in people with scleroderma. Findings from the 12 patient trial, which was led by Dr. Brigitte Granel and Dr. Guy Magalon of the Assistance Publique des Hôpitaux de Marseille in France, is titled “Autologous…

Sunshine Heart, Inc., an early-stage medical device company focused on developing, manufacturing and commercializing the C-Pulse System for treatment of Class III and ambulatory Class IV heart failure, has announced the start of a research collaboration with Dr. Mark Slaughter and the University of Louisville to explore the technology’s potential benefits for…

A recent review, entitled “Medical treatment update on pulmonary arterial hypertension,” presents the latest research for three new drugs that have been approved by the US FDA to treat PAH. The review, which is published in Therapeutic Advances in Chronic Disease, highlights the mechanisms of action for the…

Research scientists at Bayer HealthCare AG in Germany are optimizing a new chemical inhibitor for pulmonary arterial hypertension (PAH) treatment. The team of medicinal chemists generated a library of compounds centered around inhibiting human neutrophil elastase (HNE), a key driver of inflammation in PAH. After generating molecules that successfully inhibited…

The recent announcement of positive results for the AMBITION trial testing combinatorial ambrisentan and tadalafil in patients with pulmonary arterial hypertension (PAH) is bringing more attention to the need to actively recruit participants for clinical trials. Without patients and clinicians interested in trying new treatments for a currently…