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Hypoxia is the clinical manifestation of loss of oxygen supply in the body, leading to difficulty in breathing. Alveolar hypoxia can cause constriction of the distal pulmonary arterioles, which leads to increased arterial pressure and pulmonary arterial hypertension (PAH). This is a common condition among people living in high altitudes,…

Drug maker Actelion has indicated that the company’s Food and Drug Administration (FDA)–approved pulmonary arterial hypertension (PAH) drug Bosentan, which is also known under the brand names of Actelion and Tracleer, recently failed a key FDA postmarket test. The test, which was part of the postmarket COMPASS 2 trial, revealed that Bosentan did not reduce time…

Maxim Petrichuk / Shutterstock.com PoppyPocket founder and CEO, Julie Hydzu, has just announced her commitment to backing women’s cycling team PHenomenal Hope in an upcoming cross-country race dedicated to raising awareness on pulmonary hypertension and gathering funds for the Pulmonary Hypertension Association (PHA). It will be…

United Therapeutics Corporation has announced that Remodulin, a new treatment for pulmonary arterial hypertension (PAH) by subcutaneous and intravenous administration, has obtained a distribution permit in Japan from the country’s Ministry of Health, Labour and Welfare, the governmental body responsible for granting such approvals. Yu-Lun Lin, associate vice president and managing…

Pulmonary Hypertension (PH) is a rare condition characterized by increased pressure and constriction of the pulmonary arteries and the surrounding veins, which in turn applies excess pressure to the right side of the heart. It is a progressive condition that worsens with time if left untreated. The…

Rensselaer, New York-based biopharmaceutical company Pulmokine recently made a major announcement regarding the company’s efforts in developing a novel therapy for pulmonary arterial hypertension (PAH). In a press release from late March, Pulmokine indicated that that the National Heart, Lung, and Blood Institute (NHLBI), a division of the federally run National…