The nutritional supplement N-acetylcysteine (NAC) may have immunomodulatory and cardioprotective properties, which can potentially benefit pulmonary hypertension patients, according to the recent study “N-acetylcysteine improves established monocrotaline-induced pulmonary hypertension in rats,” conducted by Dr. Marie-Camille Chaumais, at the University of Paris-Sud, College of Pharmacy, France. As the pathophysiology of pulmonary arterial hypertension…
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Biothech company Bellerophon Therapeutics met the enrollment goal for its Phase 2 clinical trial evaluating INOpulse in patients with pulmonary arterial hypertension. Eighty patients, with age limits of 16-80 years, were enrolled at 52 sites across the United States and Canada. INOpulse is pulsed, inhaled nitric oxide.
The American College of Chest Physicians (CHEST) has announced updates to its Pulmonary Arterial Hypertension guidelines in the online publication of “Pharmacological Therapy for Pulmonary Arterial Hypertension in Adults: CHEST Guideline” (Chest. 2014;145(5):1055-1063. doi:10.1378/chest.13-1864) in the journal CHEST. Pulmonary arterial hypertension (PAH) is a rare form of pulmonary…
Actelion Ltd. met the primary endpoint of its pivotal Phase 3 clinical trial of selexipag in pulmonary arterial hypertension (PAH) patients. Morbidity and mortality were decreased in patients dosed with selexipag relative to placebo. “I am overwhelmed by the result of this long-term outcome study that evaluated selexipag in…
The Pulmonary Hypertension Association (PHA) is hosting the 2014 International PH Conference and Scientific Sessions, in what is expected to be the largest gathering of the pulmonary hypertension community in the world. Leaders of PH associations from around the globe will join patients, caregivers, families, nurses, and other…
For those with PAH, treating inflammation associated with the disease could be the next step in improving quality of life and reducing the mortality rate. Reata Pharmaceuticals has enrolled the first patients in a Phase 2 clinical trial to assess the safety, tolerance, and efficacy of…
Evaluating pulmonary arterial hypertension patients for heart performance parameters during exercise shortly after diagnosis allows for a good indication of the chance of survival for the patient, as noted in a study published in European Respiratory…
A group of researchers from Turkey improved the health of an 18-year-old patient using a homemade fenestrated atrial septal occluder. They published their study in BioMed Central with the…
Chronic thromboembolic pulmonary hypertension (CTEPH), a disease caused by unresolved pulmonary blood clots, is a major contributor to pulmonary hypertension. Previous reports have identified that…
Team PHenomenal Hope is one of the cycling teams that is set compete in a high-endurance cycling event called Race Across America (RAAM). However, their goal is not winning, but raising awareness for pulmonary hypertension (PH), a rare and debilitating lung disease that can be deadly. The race begins June,…
Bayer HealthCare recently announced it will test the efficacy and safety of the drug Riociguat in patients with symptomatic pulmonary hypertension (PH) associated with idiopathic interstitial pneumonias (IIP). The study will take place at more than 50 sites in 11 countries and will include about 120 patients. Designed…
Swiss biotech company Actelion Pharmaceuticals has launched Opsumit (macitentan) as a new treatment option for patients with pulmonary arterial hypertension (PAH) in England, where approximately 3,000 people receive disease-targeted drug therapy for the condition. This comes as significant news for Actelion, after the Institut National d’Excellence en Santé…
