News

Gene Activity Analysis of Whole Blood Finds 3 Major PAH Subgroups

Gene activity analysis of whole blood collected from people with pulmonary arterial hypertension (PAH) identified three patient subgroups associated with distinct clinical features and outcomes, a study concluded. These findings may provide molecular insights into the development of PAH, improve disease risk assessments, and potentially guide individual treatment strategies,…

CTEPH Study Ties Lung Arterial Obstruction to Airflow Obstruction

Increased lung arterial obstruction is significantly associated with greater airflow obstruction in people with chronic thromboembolic pulmonary hypertension (CTEPH) and without a smoking history, a study shows. Notably, airflow obstruction, reflected by a reduced ability to exhale quickly, was lessened with reduced arterial obstruction and improved blood flow following…

Pulmonary Hypertension Tied to Increased Cancer Risk

People with pulmonary hypertension are at increased risk of developing cancer, especially lung and skin cancers, a new study indicates. The study, “Pulmonary hypertension is associated with an increased incidence of cancer diagnoses,” was published in the journal Pulmonary Circulation. Pulmonary hypertension (PH) refers to…

Tenax Plans Phase 3 Trial of TNX-201 for Later This Year

Tenax Therapeutics has completed a pharmacological assessment of TNX-201, the company’s new oral formulation of imatinib for pulmonary arterial hypertension (PAH), in healthy volunteers. The assessment included comparisons against Gleevec, another oral formulation of imatinib sold by Novartis that is approved to treat certain blood cancers, but was…

Top 10 Pulmonary Hypertension Stories of 2021

Pulmonary Hypertension News brought you the latest coverage of advances in treatment, clinical trials, and scientific research related to pulmonary hypertension (PH) throughout 2021. We look forward to continuing to report more news to patients, family members, and caregivers dealing with PH in the new year. Here are the…

Specialty Care Can Lower Need for Hospitalization With PH-HFpEF

Care at a specialty center is tied to a lower risk of hospitalization for people with heart failure with preserved ejection fraction (HFpEF) who have pulmonary hypertension, according to a new study. The study, “Improved Hospitalization Rates in a Specialty Center for Heart Failure with Preserved Ejection Fraction…