News

Opsumit-Adcirca Combo Improves Blood Flow and Physical Capacity in People New to PAH, Trial Data Show

A combination of Opsumit (macitentan) plus Adcirca (tadalafil) lowered pulmonary vascular resistance — a measure showing how well blood flows through vessels — by 47% in people newly diagnosed with pulmonary arterial hypertension (PAH) and improved their physical capacity, new data show. Olivier Sitbon, MD, PhD, with Université Paris–Sud presented the…

Positive Data Supports Advancing Rodatristat Ethyl to Phase 2 Trials in PAH Patients, Altavant Says

Oral treatment with rodatristat ethyl is safe and well-tolerated, according to results from two completed Phase 1 clinical studies in healthy volunteers. These positive results support advancing the investigational therapy into Phase 2 studies involving people with pulmonary arterial hypertension (PAH), the treatment’s developer says. The most recent…