News

Low-dose Whole Body Irradiation May Reverse the Development of PH, Mouse Study Suggests

Low-dose radiation given to two mouse models of pulmonary hypertension depleted disease-causing cells, preventing and reversing the development of the condition, researchers report. Their study, “Low dose 100 cGy irradiation as a potential therapy for pulmonary hypertension,” was published in the Journal of Cellular Physiology. Pulmonary hypertension (PH) develops due to…

Poor Heart Function Raises Risk of Early Death After Lung Transplant for IPAH Patients, Study Suggests

Certain parameters of poor heart function are risk factors for early death among idiopathic pulmonary arterial hypertension (IPAH) patients who undergo lung transplant, a small Chinese study suggests. The study, “Risk Analysis of Perioperative Death in Lung Transplant Patients With Severe Idiopathic Pulmonary Hypertension,” was published in the journal…

Nonprofit Group Works to Raise Rare Disease Awareness in India

With an estimated 1.37 billion inhabitants, India will likely surpass China in five years as the world’s most populous country. That also means it will have more rare-disease patients than any nation. It already has more than twice as many as the 28-member European Union. Harsha K. Rajasimha, a genomics…

NT-proBNP Levels Can Predict Long-term Outcomes and Treatment Response in PAH Patients, Study Says

Levels of NT-proBNP can predict long-term outcomes and response to treatment with Uptravi (selexipag) in patients with pulmonary arterial hypertension (PAH), a post-hoc analysis of the Phase 3 GRIPHON trial shows. The study, “Association of NT-proBNP and Long-Term Outcome in Patients with Pulmonary Arterial Hypertension: Insights from the Phase III…