News

PH-Targeted Therapies Show Modest-at-Best Benefit in PH Due to Left Heart Disease, Review Study Reports

A large review of clinical trials evaluating whether pulmonary hypertension (PH)-targeted therapies can improve exercise capacity in patients with pulmonary hypertension due to left heart disease (PH-LHD) found varying effectiveness and modest benefit. The findings were reported in the study “Pulmonary hypertension-targeted therapies in heart failure: A systematic…

Bellerophon’s Clinical Trials for INOpulse PH Therapies Moving Forward

Bellerophon Therapeutics has announced positive data from its Phase 3 clinical trial investigating INOpulse in patients with pulmonary arterial hypertension (PAH), as well as the enrollment of the first group of patients in its Phase 2b study testing INOpulse in patients with pulmonary hypertension associated with interstitial lung…

Inspiratory Muscle Weakness Aggravates Shortness of Breath in CTEPH Patients, Study Shows

Inspiratory muscle weakness aggravates shortness of breath caused by exertion and lung function capacity in patients with chronic thromboembolic pulmonary hypertension, a study has found. The study, “Inspiratory muscle weakness contributes to exertional dyspnea in chronic thromboembolic pulmonary hypertension,” was published in the journal PLOS One. CTEPH is a…

Arterial Stiffness May Be Prevalent in CTEPH Patients, Small Study Suggests

Arterial stiffness, a marker of atherosclerosis, is significantly greater in patients with chronic thromboembolic pulmonary hypertension (CTEPH) compared to people with other diseases that also put them at risk of atherosclerosis, researchers report. The study, “Increased systemic arterial stiffness in patients with chronic thromboembolic pulmonary hypertension,” was published…