News

Obese people with pulmonary arterial hypertension (PAH) are less likely than patients of normal weight to die while hospitalized, finds a study examining the so-called “obesity paradox.” The study, ... Read more

July 19, 2017July 19, 2017

Many Scleroderma Patients Progress Slowly Toward PAH, Four-year Study Indicates

News, PAH News

The exercise capacity of people with scleroderma who have yet to develop pulmonary arterial hypertension (PAH) diminishes over time, according to an Austrian study. Their lung function during exercise also ... Read more

July 18, 2017July 18, 2017

Mount Sinai, Theragene Form Partnership to Move Potential PH Gene Therapy to Clinical Development

News, PH News

New York’s Mount Sinai and Theragene Pharmaceuticals have joined efforts to move a novel investigational aerosol-delivered gene therapy to treat pulmonary hypertension (PH) into a clinical development program. The new therapy, ... Read more

July 17, 2017July 17, 2017

Arena Pharmaceuticals Announces Positive Results for Ralinepag in PAH Patients

News, PAH News

Arena Pharmaceuticals has announced positive results for ralinepag (APD811), an investigational prostacyclin receptor agonist being investigated in a Phase 2 trial to treat pulmonary arterial hypertension (PAH). Ralinepag is an oral ... Read more

July 14, 2017July 14, 2017

Aironite Mist Lowers Blood Pressure in Hearts of Pulmonary Hypertension Patients, Trial Update Shows

News, PH News

Savara’s inhaled sodium nitrite therapy Aironite lowered blood pressure in the upper and lower heart chambers and pulmonary artery of pulmonary hypertension patients, according to an update of a ... Read more

July 12, 2017July 12, 2017

Extended Release Formulation of PAH Therapy Ralinepag Shows Promise in Phase 1 Trial

News, PAH News

Results of a Phase 1 clinical study in healthy volunteers evaluating different formulations of Arena Pharmaceuticals’ prostacyclin receptor agonist, ralinepag, for the treatment of pulmonary arterial hypertension (PAH), showed ... Read more

July 10, 2017July 10, 2017

Adipsin Protein Is a Biomarker of PAH Associated with Systemic Sclerosis, Study Finds

News, PAH News, PH News

Elevated levels of a protein called adipsin, produced by adipose or fat tissue, was found to be associated with an increased risk of pulmonary arterial hypertension (PAH) and associated cardiovascular ... Read more

July 7, 2017July 7, 2017

SteadyMed Submits New US Drug Application for PAH Treatment Trevyent

News, PAH News

SteadyMed Therapeutics submitted a new drug application (NDA) to the U.S. Food and Drug Administration (FDA) for Trevyent (treprostinil injection) in the treatment of pulmonary arterial hypertension (PAH), SteadyMed’s partner, Cardiome Pharma, recently announced. ... Read more

July 5, 2017July 5, 2017

Bayer Launches New Trial to Assess Switch from Certain Inhibitors to Adempas in PAH Patients

News

Bayer has launched a Phase 4 clinical trial called REPLACE to evaluate Adempas (riociguat) in patients with pulmonary arterial hypertension (PAH) who do not respond properly to treatment with certain inhibitors ... Read more

June 30, 2017June 30, 2017

Higher Mortality After Bilateral Lung Transplant in Patients with Both COPD and Pulmonary Hypertension, Study Finds

News, PH News

Pulmonary hypertension (PH) in patients with chronic obstructive pulmonary disease (COPD) was associated with higher mortality rates after bilateral lung transplantation (transplantation of both lungs), but not after single ... Read more