News

September 22, 2017September 22, 2017

Amended Collaboration Deal Gives Acceleron the Global Rights to Potential PAH Therapy Sotatercept

News, PAH News

Celgene has given Acceleron Pharma the global rights to develop and commercialize sotatercept as a treatment for pulmonary arterial hypertension (PAH) and other lung diseases. Acceleron obtained the rights under a revision of ... Read more

September 20, 2017September 20, 2017

Diethylcarbamazine, an Anti-parasitic Therapy, Prevents PH in Mice, Brazilian Study Finds

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Diethylcarbamazine, a compound used to fight a tropical parasitic disease, might effectively treat pulmonary hypertension (PH), a Brazilian research team concluded after observing the drug’s effect on mice. Their study, “Diethylcarbamazine: A potential ... Read more

September 19, 2017September 19, 2017

Estrogen Reversed PH in Rat Study, Offering Clues to Disease Mechanisms

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The female sex hormone estrogen may prevent disease progression of pulmonary hypertension — at least if results in rats can be translated to human patients. Researchers at the University of ... Read more

September 18, 2017September 18, 2017

Adempas May Benefit PAH Patients Who Fail to Respond to PDE5 Inhibitors, Trial Indicates

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Bayer’s Adempas (riociguat) can improve the lung and heart functioning of pulmonary hypertension patients who fail to respond to phosphodiesterase-5 inhibitors (PDE5i), a Phase 3 clinical trial suggests. The RESPITE trial ... Read more

September 15, 2017September 15, 2017

Study Examines Risk Factors Between Pulmonary Arterial Hypertension and SLE

News, PAH News

Pulmonary arterial hypertension (PAH) is a rare complication of systemic lupus erythematosus (SLE) and is associated with the presence of specific autoantibodies, a study has found. PAH is a complex ... Read more

September 13, 2017September 13, 2017

New Model of Intensive Care Breathing Specialists Working with Heart Doctors Is Promising, Study Reports

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Doctors who are intensive care respiratory specialists help seriously ill heart patients with breathing difficulties achieve better outcomes, a University of Maryland School of Medicine study reports. Researchers said the new ... Read more

September 12, 2017September 12, 2017

Uptravi Improves Connective Tissue Disease-Associated PAH, Regardless of Disease Subtype, Trial Shows

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Uptravi (selexipag) slows the progression of connective tissue disease associated with pulmonary arterial hypertension, regardless of the type of connective tissue disease, according to a Phase 3 clinical trial in ... Read more

September 11, 2017September 11, 2017

Pulmonary Hypertension Survival Rates Vary with Cause of Disease, German Study Finds

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Information from a pulmonary hypertension registry at Germany’s University Hospital Giessen indicates that patient survival rates vary with the cause of their disease. Researchers published the results in The Journal of Heart and ... Read more

September 9, 2017

Vascular BioSciences Wins Grant to Study Peptide For Pulmonary Hypertension

News

Vascular BioSciences (VBS) received a Fast-Track STTR grant of up to $2.3 million to begin a Phase I/II study that will examine CARSKNKDC (CAR) peptide’s efficacy for pulmonary hypertension (PH). The study, ... Read more

September 8, 2017September 8, 2017

Bellerophon’s INOpulse Shows Promise in Phase 2 Clinical Trial for PH-COPD

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Bellerophon recently announced promising results in a trial assessing INOpulse, its investigational treatment device for pulmonary hypertension associated with chronic obstructive pulmonary disease (PH-COPD). Results showed the device led to an average ... Read more