News

August 22, 2017August 22, 2017

Estrogen Inhibitors Can Prevent and Treat PAH in Mice, Vanderbilt Study Finds

News, PAH News

Estrogen inhibitors may treat pulmonary vascular disease by correcting metabolic defects in women with pulmonary arterial hypertension (PAH), say researchers at Nashville’s Vanderbilt University. Their study,“Oestrogen inhibition reverses pulmonary arterial hypertension ... Read more

August 21, 2017August 21, 2017

Lab Study Shows Positive Effects of Adcirca in Treatment of PAH

News, PAH News

Adcirca (tadalafil) exerts a variety of positive effects that may explain why the therapy improves idiopathic pulmonary arterial hypertension (IPAH), according to an in vitro study. The study, “Tadalafil ... Read more

August 18, 2017August 18, 2017

Sprycel-induced PAH Seen to Persist for Years in Sizable Number of Leukemia Patients in Study

News, PAH News

A treatment given people with chronic myelogenous leukemia (CML) — Sprycel (dasatinib) — is known to cause pulmonary arterial hypertension (PAH) in some. Now, researchers in France report that PAH ... Read more

August 16, 2017August 16, 2017

Reviva’s RP5063 Prevented Rats from Developing Pulmonary Hypertension, Study Reports

News, PAH News

Reviva Pharmaceuticals‘ RP5063 prevented rats from developing pulmonary arterial hypertension (PAH), according to a Canadian study. In addition to precluding heart and blood vessel damage in the animals, RP5063 decreased levels ... Read more

August 15, 2017August 15, 2017

Bellerophon Updates Pulsed, Inhaled Nitric Oxide Clinical Trials for PH, Related Disorders

News

Bellerophon Therapeutics has updated clinical trials testing its investigative INOpulse system for several forms of pulmonary hypertension (PH). The update is part of the company’s second-quarter 2017 financial report. The INOvation-1 trial ... Read more

August 14, 2017August 14, 2017

Tracking Long-term Changes in PAH Patients’ Heart Conditions Could Help Reduce Deaths, Study Suggests

News, PAH News

Tracking long-term changes in measurements associated with pulmonary hypertension patients’ death from heart disease can help doctors do a better job of identifying those at higher risk of such ... Read more

August 11, 2017

Human Cardiotrophin 1 Protein Improves Heart Function in Rats with PAH, Study Shows

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Human cardiotrophin 1 protein (hCT1) stimulates heart muscle growth in rats with induced right heart failure (RHF) due to severe pulmonary arterial hypertension, leading to improved heart function, a new study shows. The ... Read more

August 9, 2017

PHA Expands Network of Centers for Comprehensive Care

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The Pulmonary Hypertension Association (PHA) has expanded its Pulmonary Hypertension Care Centers (PHCC) network by accrediting two new pulmonary hypertension (PH) programs as Centers for Comprehensive Care (CCC). The ... Read more

August 8, 2017August 8, 2017

How a PH Support Group in Loma Linda, California, Helps Patients Cope and Exchange Information

News, PH News

Pulmonary hypertension expert Paresh Giri believes in patient support groups. The prevailing view is that the groups’ main function is helping patients cope with their condition. They certainly do that, ... Read more

August 7, 2017

Combination of Biomarkers Identified That Predicts Disease Progression in IPH

News

The ratio between the proteins MMP2 and TIMP4 in blood samples of idiopathic pulmonary arterial hypertension (iPAH) patients was found to predict disease worsening and mortality in a German study. ... Read more