News

IPAH disease worsening linked to 2 tumor biomarkers: Study

Elevated levels of two tumor biomarkers, AFP and CA125, were found to predict disease worsening in people with idiopathic pulmonary arterial hypertension (IPAH) in a new study from China. “Changes in AFP over time serve as an indicator of disease alteration, enabling detection of disease progression or treatment response,”…

Gradient enrolls 1st patient in study of ultrasound-based catheter device

Gradient Denervation Technologies has enrolled the first patient in a clinical study of an ultrasound-based catheter device for the treatment of pulmonary hypertension (PH) caused by left heart disease. The PreVail-PH2 (NCT06052072) study is evaluating the feasibility of the minimally invasive device in delivering therapeutic ultrasound energy…

Algorithm may help diagnose PH when echocardiography uncertain

An algorithm based on artificial intelligence (AI) and machine learning may help in diagnosing pulmonary hypertension (PH), a new study shows. Its findings are particularly important for people suspected of having PH but whose disease remains uncertain using echocardiography, a noninvasive imaging method to examine heart structure and function.

PHA hits Houston April 6-7 to heighten pulmonary awareness

The Pulmonary Hypertension Association (PHA) will host a free workshop and fundraiser April 6-7 in Houston to raise awareness for pulmonary hypertension (PH) and support the greater PH community. The highlight of the weekend’s activities, which are aimed at educating, empowering, and supporting patients and caregivers, will be…

Tenax acquires global rights to oral, subcutaneous levosimendan

Tenax Therapeutics has secured global rights to oral and subcutaneous (under the skin) formulations of levosimendan, a potential therapy for pulmonary hypertension and heart failure with preserved ejection fraction (PH-HFpEF). Under a licensing agreement established with Orion Corp. in 2013, Tenax acquired developmental and commercial rights of…


A Conversation With Rare Disease Advocates