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Balloon pulmonary angioplasty can pose risks for CTEPH patients

Older age and high blood pressure in the pulmonary arteries raise the risk of complications with balloon pulmonary angioplasty (BPA), a second-line treatment for chronic thromboembolic pulmonary hypertension (CTEPH), a study suggested. If high blood pressure persists after surgery to remove the pulmonary arterial blood clots that cause…

Tenax receives patent for TNX-103, oral levosimendan, for PH-HFpEF

Tenax Therapeutics has been issued a U.S. patent covering oral levosimendan, also known as TNX-103, for the treatment of pulmonary hypertension and heart failure with preserved ejection fraction (PH-HFpEF). The patent (U.S. Patent No. 11,701,355) is expected to provide intellectual property protection for TNX-103 through December 2040.

Air pollution exposure linked to PH, UK population study shows

Exposure to air pollutants significantly increased the risk of pulmonary hypertension (PH), according to a U.K. population study that included almost 500,000 people. Previous or current smoking increased PH risk and mortality even further, suggesting a synergistic relationship, the researchers noted. The large-scale study, “Dynamic association…

Zymedi and NHLBI collaborate to advance ZMA001 in PAH

Zymedi is collaborating with the National Heart, Lung, and Blood Institute (NHLBI) to advance the development of its first-in-class pulmonary arterial hypertension (PAH) treatment candidate ZMA001. The South Korea-based company and the NHLBI, part of the National Institutes of Health, have signed a clinical Cooperative Research and Development…

Experts call for referral protocols to improve PH care

Note: This story was corrected July 10, 2023, to reflect that attendees at the European Cardiac and Respiratory Societies discussed the therapy Tyvaso with regard to the 2022 pulmonary hypertension diagnosis and treatment guidelines. Pulmonary hypertension (PH) experts are calling for care protocols to expedite patient referrals to…


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