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Sarcoidosis-associated Pulmonary Hypertension Is Linked to a Poor Prognosis

Pulmonary hypertension in patients with sarcoidosis is associated with poor prognosis, despite treatment with a targeted therapy, a new study shows. The study “Management and long-term outcomes of sarcoidosis-associated pulmonary hypertension,” was published in the European Respiratory Journal. Patients with sarcoidosis frequently develop pulmonary hypertension. In…

Researchers Identify Risk Factors for PAH Progression in SSc-PAH patients

Male gender and lung function parameters have been identified as risk factors for progression of pulmonary arterial hypertension in patients with systemic sclerosis-PAH (SSc-PAH), a study shows. Part of the larger, multi-center, DETECT study, these results are reported in the research, “Factors associated with disease progression in early-diagnosed pulmonary arterial hypertension…

PDE5 Blocker May Be an Effective Therapy for Early PH After Heart Attack, Study Suggests

Blocking the enzyme phosphodiesterase 5 (PDE5) is a potential new therapeutic strategy to treat early pulmonary hypertension (PH) in patients who have had a heart attack, a study suggests. The research, “Pulmonary vasodilation by phosphodiesterase 5-inhibition is enhanced and nitric oxide-independent in early pulmonary hypertension after myocardial infarction,”…

FDA Approves Third Generation Nebulizer for Tyvaso Inhalation System

The U.S. Food and Drug Administration (FDA) has approved a new, third-generation inhalation device, the TD-300/A, for use with Tyvaso (treprostinil) Inhalation Solution, United Therapeutics Corporation announced. Tyvaso is a prostacyclin vasodilator indicated for the treatment of pulmonary arterial hypertension (PAH) to improve exercise ability. Tyvaso was…