Underweight infants with pulmonary hypertension (PH) are at increased risk of developing retinopathy of prematurity (ROP), a leading cause of childhood blindness, according to a study. However, the prevalence of severe ROP was 18% lower in PH infants who received treatment with inhaled nitric oxide (iNO). “While iNO is…
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The European Patent Office has given Tenax Therapeutics notice that it plans to grant a patent covering the use of levosimendan and its active metabolites to treat pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF), the company said. TNX-103, an oral formulation currently in Phase…
Allrock Bio has raised $50 million in financing to support the clinical development of pulmonary hypertension (PH) treatment ROC-101. The company said it will use the funds to launch a Phase 2a clinical trial to test ROC-101 in people with pulmonary arterial hypertension (PAH) or pulmonary hypertension associated…
Phaware, a global advocacy organization, is launching a special podcast series to raise awareness of pulmonary arterial hypertension (PAH) caused by the use of methamphetamine, a stimulant drug known for its psychoactive effects. Methamphetamine-induced PAH is now known simply as Meth-PAH. The six-episode series, part of the “…
Pulmonary endarterectomy (PEA), a surgery to remove blood clots in individuals with chronic thromboembolic pulmonary hypertension (CTEPH), may be more effective in improving pulmonary circulation and heart function than balloon pulmonary angioplasty (BPA), according to a recent study. After treatment, a higher proportion of patients in the BPA group…
Stanford University has been awarded a grant from the U.S. National Institutes of Health (NIH) to begin a Phase 2 clinical trial of pulmonary arterial hypertension (PAH) treatment tiprelestat, the treatment’s developer announced. Tiakis Biotech said tiprelestat was found to be safe in earlier clinical trials involving more…
Corvista Health’s point-of-care device can detect cases of pulmonary hypertension (PH) that other noninvasive diagnostic tools miss, according to a recent case series. “By enabling physicians to identify pulmonary hypertension within minutes, non-invasively, and even when traditional tests fail, we are offering a new standard of care that…
Japan’s Ministry of Health, Labour and Welfare (MHLW) has granted orphan drug designation to mosliciguat, an investigational inhalation therapy that Pulmovant is developing to treat pulmonary hypertension associated with interstitial lung disease (PH-ILD). The MHLW gives this designation to experimental medicines intended to treat conditions affecting fewer than…
People with pulmonary hypertension (PH) face significant obstacles when seeking timely care, with barriers arising at each stage from symptom onset through diagnosis and treatment, according to interviews with patients and healthcare providers. Those barriers included a lack of PH knowledge among non-specialists, symptoms being dismissed, and limited access…
United Therapeutics and Mannkind Corporation are teaming up to develop a new inhaled therapy for pulmonary hypertension. The two companies worked together to develop Tyvaso DPI, a dry powder formulation that was approved in the U.S. in 2022 to improve exercise ability in people with…
Cereno Scientific has received fast track designation from the U.S. Food and Drug Administration (FDA) for CS1, its therapy candidate for pulmonary arterial hypertension (PAH). “We are very pleased to have achieved Fast Track designation for CS1, which both validates the strength of our CS1 program and supports…
At diagnosis, Black people with pulmonary arterial hypertension (PAH) tend to have more severe disease than their non-Black counterparts, a new U.S. study shows. The study, done using data from the University of Illinois Health Pulmonary Hypertension Clinic, further indicated that Black people being evaluated for PAH also tend…
