News

US Pulmonary Hypertension Association Joining Global Awareness Campaign

The Pulmonary Hypertension Association (PHA) is joining Periwinkle Hearts Around the World, an 80-organization international campaign to raise awareness of pulmonary hypertension (PH) patients’ need for better access to care. Stiffness in the lung’s arteries and veins causes the high lung blood pressure that characterizes PH. Patients experience shortness of…

Study Identifies New Gene Mutations Associated with Heritable PAH

A Japanese study of nine families members who have heritable pulmonary arterial hypertension (HPAH) found different mutations in the same gene, called BMPR2, four of which had been identified before and four newly identified. Researchers also found a new mutation in another gene, KCNK3, that caused HPAH in another family. The researchers believe…

Respira, United to Jointly Develop, License Inhaled RT234 For PH Pending FDA Approval

Two U.S. companies, Respira Therapeutics and United Therapeutics, will jointly develop and license RT234 and its dry-powder inhaler drug delivery technology AOS-DPI to treat pulmonary hypertension (PH) in the United States. Under the agreement, United, based in Silver Spring, Md., will finance the development of RT234 towards its approval by the U.S. Food and Drug…

Pulmonary Hypertension Patients Like Implanted Remodulin Delivery System

Pulmonary arterial hypertension (PAH) patients have given high marks to a new implanted,  programmable intravenous (IV) system that delivered Remodulin (treprostinil) to them with few complications, according to a clinical trial. The study, “Treprostinil Administered to Treat Pulmonary Arterial Hypertension Using a Fully Implantable Programmable Intravascular Delivery System…

US Patent Dispute Simmers Over Treprostinil-based Therapies for PAH

U.S. specialty biopharmas SteadyMed and United Therapeutics both issued media releases recently commenting on a ruling by the U.S. Patent and Trademark Office (USPTO) that declared invalid a United Therapeutics patent related to the drug treprostinil, a synthetic analogue of prostacyclin. Prostacyclin and its analogues are widely used in…

US Launch of RemoSynch Implantable Pump for PAH Postponed Until 2018

Due to regulatory delays, the U.S. launch of United Therapeutics‘s implanted pump system for the delivery of Remodulin (treprostinil) for patients with pulmonary arterial hypertension (PAH) will be postponed until 2018. “United Therapeutics’ commitment to bringing better therapies to patients transcends temporary delays or setbacks,” Martine Rothblatt, PhD,…