News

Study: New Automated Strategy May Improve Peptide Therapy in PAH

Researchers have created an automated way to engineer a more stable peptide-based therapy, which could inform the production of new and improved treatments for diseases like pulmonary arterial hypertension (PAH). The research was led by Yousef Al-Abed, PhD, co-director of the Institute of Bioelectronic Medicine at the Feinstein Institutes for…

Eosinophils Reduce Inflammation, Cell Overgrowth in PH: Study

Immune cells called eosinophils help protect against the progression of pulmonary hypertension (PH) by reducing lung inflammation and regulating the growth of muscle cells around blood vessels, a new study indicates. The study, “Eosinophils Protect Against Pulmonary Hypertension through 14-HDHA and 17-HDHA,” was published in the …

Care Center PAH Causes Differ from National Registry, Study Reveals

The identified cause of pulmonary arterial hypertension (PAH) in patients seen at a specialized care center differed substantially from national registry data, a study revealed. Most care center patients were diagnosed with PAH associated with connective tissue disorders and exposure to toxins, whereas idiopathic PAH (IPAH), of unknown cause,…

Few Liver Problems With Opsumit in PAH Patients: Real-world Data

Real-world use of Opsumit (macitentan) was generally safe, with few liver-related toxicities seen, according to data from two registries largely made up of pulmonary arterial hypertension (PAH) patients. Collective data from the two registries met a requirement from the U.S. Food and Drug Administration (FDA) for additional real-world safety…

Inhaled APN01, Potential PAH Therapy, Safe in Healthy Adults

An inhaled form of APN01 (alunacedase alfa), APEIRON Respiratory Therapies (AResT)’s investigational therapy for certain lung diseases, was safe and well-tolerated in healthy people, according to data from a Phase 1 clinical trial. “In addition to meeting all primary [goals] regarding the safety and tolerability of APN01 via a new…

Virginia Venture Partners Invests in OxiWear Device for PH

Virginia Venture Partners — Virginia Innovation Partnership Corporation (VIPC)’s equity investment program — is investing in OxiWear and its modern ear-wearable device that’s designed to continuously monitor blood oxygen levels in people with pulmonary hypertension (PH). The OxiWear device alerts the user through a phone app when there’s…