News

Congenital Heart Disease Patients Have Much Higher PH Rate, Study Shows

People with congenital heart disease are seven times more likely to develop pulmonary hypertension than the general population, a long-term Danish study indicates. In addition, congenital heart disease patients with PH are four times more likely to die than those without PH, the researchers reported. Their article, “Incidence and Mortality…

Ralinepag Reduces PAH Patients’ Risk of Death, Phase 2 Trial Shows

Arena Pharmaceuticals’ ralinepag reduced the risk of pulmonary arterial hypertension patients dying, a Phase 2 clinical trial showed. Temple University Professor Raymond Benza will present the results at the International Society for Heart and Lung Transplantation meeting in Nice, France, on April 14.  The four-day conference started April 11. The…

NIH Agency Pioneers Collaborative Research into Rare Diseases

A little-known government entity within the National Institutes of Health (NIH) is helping to lead U.S. efforts to speed up the development of therapies for some 7,000 rare diseases. The Office of Rare Diseases Research (ORDR), headquartered in Bethesda, Maryland, was established in 1993 within the NIH Office of the…

Phase 2 Trial of Levosimendan to Treat PH Linked to Specific Heart Failure Moving Forward

Plans for a Phase 2 clinical trial of levosimendan, a proposed treatment for pulmonary hypertension associated with heart failure and preserved ejection fraction, will soon be submitted to the U.S. Food and Drug Administration for approval, Tenax Therapeutics announced. In a pre-application meeting with company executives, the FDA supported the study’s proposed…

PAH Patient Outcomes Linked to Exercise Capacity

Patients with higher exercise capacity present a reduced risk of pulmonary arterial hypertension-associated death or hospitalization, according to results of a Phase 3 clinical trial. The research was published in the journal PLOS One, in a study titled “Association between six-minute walk distance and long-term outcomes in patients…

University of Virginia Pulmonary Hypertension Center Earns PHA Accreditation

The University of Virginia’s (UVA) Pulmonary Hypertension Center has been recognized as a Center of Comprehensive Care by the Pulmonary Hypertension Association (PHA). The PHA-accredited PH Care Centers initiative aims to establish an accreditation program for centers with special expertise in pulmonary hypertension (PH), particularly pulmonary arterial hypertension…